hrp0082p1-d3-127 | Fat Metabolism & Obesity (2) | ESPE2014

Infancy Lipidomic Analyses and Associations with Early Nutrition and Growth

Prentice Philippa , Koulman Albert , Matthews Lee , Acerini Carlo , Ong Ken , Dunger David

Background: Links between early life exposures and long-term health outcomes may in part be due to nutritional programming, and suggested benefits of breast feeding during infancy include reduced risk of obesity and metabolic disease. Mechanisms remain unexplained but potential differences in lipid exposures during infancy may be involved.Objective and hypotheses: To explore the effects of breast- or formula-feeding on lipidomic profiles we used recently...

hrp0094p1-33 | Fat, Metabolism and Obesity A | ESPE2021

Metabolomics in early life and the association with body composition at age 2 years

van Beijsterveldt Inge , Snowden Stuart , Myers Pernille Neve , Fluiter Kirsten de , Brix Susanne , Ong Ken , Dunger David , Hokken-Koelega Anita , Koulman Albert ,

Background and Objectives: Early life might be a critical window for adiposity programming later in life. Metabolic profile in early life may reflect this programming and correlate with later life adiposity. We investigated if metabolic profile at 3 months of age is predictive for body composition at age 2 years and if there are differences between boys and girls and between infant feeding types.Methods: In 318 healthy t...